Gene: Erap1

Gene Information

Full name endoplasmic reticulum aminopeptidase 1
Synonyms
MGI ID MGI:1933403
Viability

Phenotyping parameters

Significant Not Significant Not tested
Mortality/aging
Embryo phenotype
Reproductive system phenotype
Growth/size/body region phenotype
Homeostasis/metabolism phenotype or adipose tissue phenotype
Behavior/neurological phenotype or nervous system phenotype
Cardiovascular system phenotype
Respiratory system phenotype
Digestive/alimentary phenotype or liver/biliary system phenotype
Renal/urinary system phenotype
Limbs/digits/tail phenotype
Skeleton phenotype
Immune system phenotype or hematopoietic system phenotype
Muscle phenotype
Integument phenotype or pigmentation phenotype
Craniofacial phenotype
Hearing/vestibular/ear phenotype
Taste/olfaction phenotype
Endocrine/exocrine gland phenotype
Vision/eye phenotype

Significant Phenotype

Symbol System Phenotype Zyg Sex Age(weeks)
IMPC KMPC
Muscle phenotype Grip Strength Test   Hom Female 9W
foreleg force increase Hom Male
Hearing/vestibular/ear phenotype PPI Increase PPI Hom Female 10W
  Hom Male
ABR   Hom Female 14W
  Hom Male
Homeostasis / Metaboilsm phenotype or adipose tissue phenotype Indirect Calorimetry Decrease RER value Hom Female 11W
  Hom Male
Intraperitoneal glucose
tolerance test (IPGTT)
Decreased glucose tolerance Hom Female 11W
Increased glucose tolerance Hom Male
Skeleton phenotype X-ray   Hom Female 14W
Fracture (1/5) Hom Male
Dexa BMC per body weight, 
Lean mass decrease per body weight, 
Fat mass increase
Hom Female
Fat mass, BMD reduction Hom Male
Cardiovascular system phenotype Heart weight measurment   Hom Female 15W
Heart weight gain Hom Male
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